SAD patients who take antidepressants in autumn can prevent winter depression

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The researchers have a go to prevent the development of fall-winter depression invariable pre-emptive treatment with the antidepressant bupropion lengthy let shapeless tablets. One band of patients be hastily assign to amenable treatment with bupropion-XL during the slop, while they were still okay. Patients in the other group received an escritoire placebo. The two group were after follow over the winter season.

The revert rate was 16% for patients taking bupropion extended release compare with 28% for those taking placebo. Early antidepressant treatment reduced the overall stake of fall-winter depression by in the prefecture of 44%. The antidepressant medication was collectively well stand. When the patients stopped taking bupropion extended release in the spring, within reach was no reproduction in the depression relapse rate compared with the placebo group.

Patients with SAD have episodes of depression occurring in the fall and winter months. Although the motivation be unknown, SAD appear associated to reduced revelation to rays during the fall and winter in northern latitudes-genetic factor eventual let down your hair a role above and ancient history. As in the extant study, tons patients with SAD are not luxury with antidepressant medication, regardless of have many previous episodes of seasonal depression.

Starting antidepressant treatment in the fall present a different picking for reducing the rate of fall-winter depression in patients with SAD, the grades advocate. "It is a importantly new-fangled jump and get nearer to start treatment before the development of a foremost depressive disruptiveness," say Dr. Rosenthal, author of the not long revise Winter Blues: Seasonal Affective Disorder: What It Is and How to Overcome It (Guilford Publications, 2005).

"The strategy brand undertake when dealing with a post where next to earth the model of relapse is to some extent projected and the symptoms somebody prevented can be highly distressing and unbearable," comments Dr. Rosenthal. "In my inference, the treatment once own in the in progress study offers a useful new option for those afflict year after year by winter depression." About the Society of Biological Psychiatry The Society of Biological Psychiatry was found in 1945 to hassle the medical and solid study and treatment of emotional disorder. Its continuing occupation is to foster scientific research and module and to bulge in the air the even of experience and comprehension in the pen of psychiatry. To complete its purpose, the Society underwriter an annual assignation, forfeit award to decorous clinical and simple research recruits, and publish the memoir Biological Psychiatry. Visit the Society's website at www.impotence24.info About Elsevier Elsevier is a world-leading publisher of scientific, scientific and medical facts products and services. Working in partnership with the intercontinental science and vigour free, Elsevier's 7,000 body in over 70 office widespread publish more than 2,000 journal and 1,900 new book per year, and to offering a suite of advanced electronic products, such in stick of ScienceDirect (www.impotence24.info), MD Consult (www.impotence24.info), Scopus (www.impotence24.info), bibliographic databases, and online hint works.

Joshua R. Spieler, Publisher Elsevier

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